From the results of numerous tests performed based on the patient's history of foamy urine with significant edema for a maximum period of 5 days, the patient was diagnosed with Nephrotic Syndrome. This is a condition that occurs due to leakage in the filtration part of the kidney which leads to the leakage of a large amount of protein from the blood into the urine. This is mainly due to fluid retention known as edema, which is the result of a low level of protein in the blood. It occurs due to abnormal functioning or an affected part of the kidney (glomeruli). This syndrome can be caused by numerous diseases that come together to cause or form a particular disease; these causes range from minimal lesion disease, to membranous nephropathy, focal segmental glomerulosclerosis (FSGS) and other conditions, disorders of the glomeruli. Membranous nephropathy, also known as membranous nephritis or membranous glomerulonephritis, causes disease only in adults and is very rare in children. The leak occurs due to thickening of the membrane in the glomeruli which is the filter of the glomeruli. Focal segmental glomerulosclerosis is causative due to the formation of small scars (sclerosis) on some renal glomeruli. Another form of nephrosis cause is minimal change due to lack of virtual change detected in the glomeruli when examined under a microscope. This causes the syndrome in 9 out of a total of children under 5 years of age. The pathophysiology of nephrotic syndrome figure 4According to the test results, the patient's syndrome is caused by one of the two; minimal change and focal segmental glomerulosclerosis. The pathophysiologies of the disease are primary glomerular defect, circulating permeability factor and inhibitors. The primary glomerular defect of nephrotic syndrome leads to the loss of high molecular weight proteins equivalent to the size of albumin of approximately 66 kD, with similarly sized hemostatic proteins being pathologically excreted in the urine (Eddy AA and Symons JM, 2003). Due to these excretions; notable loss of important coagulation regulatory proteins such as antithrombin and the SA proteins mentioned above; Hypoalbuminemia is an event that occurs predominantly due to urinary protein losses. In response to this, hepatic albumin synthesis is increased but is still not sufficient to prevent the fall in serum albumin concentration. Proteinuria, proteinuria in the nephrotic range is almost invariably due to glomerular disease.