Index Huntington's DiseaseTest for DisorderConclusionDiseases caused by dynamic mutations involve an unstable causative mutation. These disorders are characterized by an uncontrolled expansion of a portion of DNA within the diseased gene made up of repeating units of three or more tandem nucleotides. Typically, polymorphic alleles are present in the genes associated with these diseases. Say no to plagiarism. Get a tailor-made essay on "Why Violent Video Games Shouldn't Be Banned"? Get an original essay Huntington's disease This condition is acquired in an autosomal dominant manner. Huntington's disease is a dynamic brain problem that causes uncontrolled development, intense arguments, and loss of the ability to think (perception). The most prevalent form of this problem, the onset of Huntington's disease in adults, usually occurs between a person's thirties and forties. Early signs and side effects may include irritability, melancholy, small automatic developments, poor coordination, and problems adapting new data or basic leadership. Many individuals develop constant jerking or jerking movements known as chorea with Huntington's disease. These movements become increasingly more complex as the disease progresses. People affected by the flu may have problems walking, talking and swallowing. Huntington's disease is caused by changes in the HTT gene. The HTT gene provides guidance on how best to make a protein called Huntingtin. Although the role of this current protein is vague, it appears to play a significant role in the brain's nerve cells (neurons). The HTT variation that causes Huntington's disease includes a DNA fragment known as the CAG trinucleotide repeat. This segment comprises a progression of three squares of DNA structure (cytosine, adenine and guanine) that appear in succession a few times. The CAG area is usually mimicked within the gene 10 or more times. Testing for the disorderPredictive: Predictive screening for the genetic mutation that triggers Huntington's disease allows people who know they are at risk to find out whether they will develop HD later. For several treatment appointments, people who want a predictive test generally need to go in person to a specialty clinic. Prenatal: Intended parents request prenatal testing when a parent is diagnosed or found to be a carrier of the Huntington's disease gene. Prenatal tests will show whether the faulty gene is inherited by the baby. ... If the fetus tests positive, the parents will decide whether to terminate the pregnancy. Theory behind the test - The discovery of the HD gene contributed to a genetic test for diagnosing or confirming Huntington's disease. Using a blood sample, counting the number of CAG repeats in the huntingtin genome, the genetic test analyzes the DNA for the HD mutation. Individuals without HD typically have 28 repeats or fewer. Please note: this is just an example. Get a custom article from our expert writers now. Get a Custom Essay Conclusion Huntington's disease is caused by a dynamic mutation in genes. Interesting fact that Adolf Hitler suffered from this disease. It is not a common disease and therefore little studied; research into its treatment and prevention is still ongoing.