The way these two civilizations ended is very different. Mesopotamia was divided into Babylon and Assyria which eventually led to the fall of the civilization. The people of the area were becoming poor and had difficulty trading with other civilizations. It is a mystery how the Indus Valley fell. Some historians believe that the descent was natural and that perhaps a change in the environment could have made it more difficult for such a large population to gather food. Another theory is that the Aryans wanted the land and wiped out the Indus people. Even though Mesopotamia and the Indus Valley had different elements that led to their downfall, they share a legacy that stands out when we talk about how intelligent and developed early civilizations were
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