Dry Beriberi and Alcoholic Neuropathy Cause and Influence Randell Jack Long Sr. Mohave Community College Author's Note Biology 100, Section 111 Professor Leonard M D'Orazio March 31, 2014 A Review of the Literature This paper outlines the cause and effects of this disorder and its connection with socio-economic status. Dry beriberi is a disease believed to be caused by malnutrition. The history of the disease is documented in China as far back as 600 BC. Dryberiberi comes from a Sinhala phrase meaning "weak, feeble." (www.wikipidia.org/wiki/beriberi) The effects of beriberi reached their peak in the late 1800s. . The disease affected lower-class minorities in East Asia. In the 1800s, Japanese cadets aboard ships were fed only rice. This resulted in many deaths due to the malnutrition they received. The highest ranking officers on those ships were fed fish, milk, and meat. Dry beriberi had negative effects on the body. Once the body is deprived of the much needed coenzyme. the body is unable to enter the citric acid cycle, thus stopping the production of ADP. According to D'Orazio (1985) “Nutritional polyneuropathy is usually characterized by progressive weakness and muscular atrophy of increasing degree which symmetrically involves the legs more than the arms and the distal muscles more than the proximal ones”. Vitamin B is essential for cellular respiration. Niacin B3 is a source of NAD+. The electron acceptor in phase 1 of the respiratory cycle. Also known as glycolesis. When it picks up the electron it becomes NADH. NADH is then converted. Priuvate will enter the citric acid cycle. It then transports the electron to the electron...... to the center of the paper...... Class ce its relation to ethanol intake.” Nutritional polyneuropathy - definition of nutritional ... (n.d.). Retrieved from http://medical-dictionary.thefreedictionary.com/nutritional+polineuropathyShy, ME. “Peripheral Neuropathies In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, PA: Saunders Elsevier; 2007: ch 446William, RH and Bissel, GW “Thiamine metabolism with particular reference to the role of the liver and kidneys. Bow. Internal med. 73: 203, 1944.http://www.cdc.gov/nchs/fastats/alcohol.htmhttp://www.neuropathysupportnetwork.org/neuropathyfaq.#14http://www.wikipedia.org/wiki.beriberihttp:/ /www.ninds.nih.gov/disorders/peripheralneuropathy/detail_peripheralneuropahttp://www.gotcore.net/what-is-neuropathy.htmlhttp://wwwmybwmc.org./library/1/000593http://nature.com/ ejcn/journal/v56/full/16013120.html