For humans, having a healthy immune system is essential. Our immune system is important because it helps the body to fight any foreign bacteria, viruses and diseases by attacking it, which is why we must take care of it as much as possible by strengthening it. But this so-called defense system can also cause problems such as attacking another individual's donated organs or blood, unless the organs or blood are carefully matched. It may also overreact to harmless invaders such as pollen grains, which can cause hay fever, and in some cases, the immune system may turn against the body's own cells. The immune system uses different types of white blood cells. Some of these cells, called macrophages, constantly patrol the body to destroy any germs that enter. In the event that an infection takes hold, the body will begin to react with a very powerful defense of T and B cells. These cells give people acquired immunity to prevent the same germ form from making them sick again. Unfortunately, with today's environmental problems, people are facing various health problems, especially in terms of the immune system. Air pollution, which is one of the major environmental problems, can cause numerous health risks. Exposure to air pollutants can have a high probability of causing long-term effects on people, as well as blocking the immune system. Therefore, pollution in the air can affect the immune system by weakening it and making it much more vulnerable to foreign invaders, diseases, harmful bacteria and viruses. There are different types of toxins and pollutants in the air that contribute to the serious environmental issue of air pollution. One of these major toxins is dioxin, a highly toxic compound... half of the paper... these health situations occur. In conclusion, air pollution affects the immune system, making it weak and vulnerable to certain bacteria, diseases, viruses and foreign invaders. The most common diseases that are most affected include asthma and allergies. Air pollution in general has been observed to change the immune system's ability to handle particular allergens. Exposure to toxins such as dioxin can cause serious health problems for people. Long-term exposure to this toxin is linked to weakening of the immune system, as well as the nervous system, endocrine system and some reproductive functions. So, everyone has a particular level and exposure to dioxins in the body. Improving air quality is the key answer to avoiding any type of disease development, but it is a long-term goal that will require help and commitment at national and global levels..